Chronic poverty and disability in Uganda are inextricably linked. Despite impressive economic gains made by the country, majority of disabled people are miserably poor. This study investigated the perception of People with Disabilities (PWDs) towards Operation Wealth Creation (OWC) services, a government program aimed at alleviating poverty. A cross-sectional survey was adopted to collect data from 66 PWDs. Descriptive statistics such as frequency count, means and percentages were used to characterize PWDs and their accessibility to OWC services. A logistic regression model was run to establish the influence of socio-economic and institutional characteristics of PWDs on accessibility to services offered by the OWC. Perception of PWDs towards OWC services was as well measured using of a 5-point Likert scale. The binary logistic econometric model was applied for analyzing factors influencing perception of PWDs towards OWC services. Results showed that majority of PWDs (57.58%) were males with average age of 35years. Primary was the highest level (56.06%) of education and 96.97% of them were married with average land size was 1.39acres. 42.42% were ranging between 1-10 years of farming. Most of the PWDs (71.21%) positively perceived services by the OWC. Logistic regression analysis revealed that age (P≤0.05), farm size (P≤0.05), and extension contact (P≤0.01) had positive and significant influence on accessibility of PWDs to OWC services, whereas, farming experience (P≤0.05), participation in other off farm (P≤0.05) and distance to the nearest market (P≤0.01) negatively and significantly influenced accessibility of PWDs to OWC services. Logistic regression analysis showed that the coefficient of access to extension services (P≤0.01), farm size (P≤0.05) and farming experience (P≤0.05) positively and significantly influenced perception of PWDs towards OWC services. Distance from the nearest market (P≤0.05) and age (P≤0.05) negatively and significantly influenced ........