EAS Publisher | Detection of New Delhi Metallo-Β-Lactamase Production from Klebsiella pneumoniae Isolated from Clinical Samples

Detection of New Delhi Metallo-Β-Lactamase Production from Klebsiella pneumoniae Isolated from Clinical Samples

DOI : https://doi.org/10.36349/easjpid.2021.v03i04.002

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The rapid spread of New Delhi metallo-β-lactamase (NDM) production in Klebsiella pneumoniae proved to be a major challenge for the treatment and control of infectious diseases. The aim of the study was to detect New Delhi metallo-β-lactamase production in Klebsiella pneumoniae isolated from clinical samples. A total of 103 clinical samples were collected and analysed for the presence of Klebsiella pneumoniae was isolated from 26 (25.2%) of the clinical samples. Antibiotic susceptibility testing was carried out for all the isolates. Out of the 26 isolates screened, only 3 and 5 were resistant to meropenem and imipenem respectively. These isolates were screened for New Delhi metallo-β-lactamase production using the combined-disk test. The 8 isolates were New Delhi metallo-β-lactamase producer. New Delhi metallo-β-lactamase producing Klebsiella pneumoniae in Plateau State Specialist Hospital Jos, Plateau State, Nigeria as seen in this study occurs at the rate of 30.8%. Having established the presence of New Delhi metallo-β-lactamase among patients in Plateau State Specialist Hospital, Jos, efforts should be geared towards limiting their spread.

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