Introduction: Knee joint is the numerous structures within it and their various pathologies, which result in pain and many other symptoms such as instability and restriction in range of motion. There have been numerous studies studying accuracy of the MRI of the knee, there has been only a few that have fully investigated the diagnostic accuracy of the MRI in patients with an acute ACL injury, thus the present study aims to assess role of magnetic resonance imaging (MRI) in diagnosis of anterior cruciate ligament (ACL) tears in patients with internal derangements of knee. Aim: The research aims to assess role of magnetic resonance imaging (MRI) in diagnosis of anterior cruciate ligament (ACL) tears in patients with internal derangements of knee. Methodology: This cross-sectional study was completed from December 2020- March 2021 at Department of Radiology of Tertiary Care Hospital. The 40 female patients with any age were made part of the study with painful or unstable knee joint. Clinical examination was performed after recording demographic data. MRI was performed and primary and secondary signs were noted for each case. SPSS 17 was used for the analysis of data. Results: The majority of the patients were male (n=29; 72.5%), whereas only 11 (27.5%) females. On findings regarding complete/partial ACL, 57.5% participants responded with complete ACL, whereas 42.5% with partial ACL. Conclusion: Accurate and non-invasive methods for the ligamentous injury evaluation are magnetic resonance imaging. In patients with soft tissue injuries to the knee, it might be performed as a first line examination.