Introduction: Renal colic is a form of stomach discomfort that is usually caused by ureter blockage by dislodged renal stones. In suspected cases of acute renal urolithiasis and acute flank pain, computed tomography (CT) of the kidney, ureter and bladder (KUB) is being employed more and more in place of intravenous urography or KUB radiography due to its higher accuracy. Aim: The present study aims to assess the role of unenhanced multidetector computed tomography (CT) of kidneys, ureter and bladder (KUB) in the initial imaging of suspected acute renal colic. Methodology: This study was performed from December 2020 to March 2021 at Gujranwala Division. 138 cases of suspected acute renal colic underwent CT KUB. The demographic data, radiological data, clinical information and follow up data were recorded for each patient. The statistical package for social sciences (SPSS) v.17 was used to perform descriptive analysis. Results: There were 91 (53.5%) male and 79 (46.5%) females included in the present study with mean age of 50.86 ± 18.57 years. Out of 170 patients, only 138 (81.17%) were indicated with acute findings, whereas 32 (18.82%) individuals showed no acute findings. Majority of the stones had location near the pelvic brim (n=47; 27.6%). Conclusion: The use of CT KUB should be encouraged for evaluation of renal colic.