Background: The recent COVID 19 pandemic has imposed threats on both metals as well as physical health since its ferocious outbreak. This is a new but one of the most serious pandemics in the world now. Although this disease is responsible for very limited symptoms and complications like severe acute respiratory syndrome, fever, headache, diarrhea, malaise, and weakness but its probability of affecting more people is very high. Now it seems COVID 19 is dictating the whole world community. Even OPD patients who have already reached a hospital are not free from the mental and physical health effects of the Covid 19 pandemic. Aim of the study: The aim of this study was to assess the mental and physical health effects of the Covid 19 pandemic among OPD patients. Methods: This was a prospective interview-based study which was conducted in the Department of Medicine Enam Medical College and Hospital, Savar, Bangladesh during the period from July 2020 to December 2020. In total 118 patients with several health problems, physically or virtually attended the OPD of the mentioned hospital were enrolled as the study population. This study was approved by the ethical committee of the mentioned hospital. A pre-designed questionnaire was used in patent data collection. All data were processed, analyzed, and disseminated by MS Office and SPSS version as per need. Result: In this current study, in analyzing the effects on the mental health of participants we observed the feeling of suffocation, feeling of exhaustion, fear of falling ill, anxiety about the future, and feeling of loneliness was found as some major negative mental impacts of Covid 19 on the respondents which were among 12.71%, 11.02%, 8.47%, 7.63% and 6.78% participants respectively. On the other hand, in analyzing the physical health effects among participants we found 22.03%, 14.41%, 8.47%, 5.93%, and 3.39% of participants were with the feeling of physical fatigue, gaining extra body weight, insomnia, general.......