EAS Publisher | Effects of Citrus aurantifolia (Lime) and Camellia sinensis (Lipton Tea) Decoction on Some Plasma Electrolytes and Creatinine Concentration in Female Albino Rats

Effects of Citrus aurantifolia (Lime) and Camellia sinensis (Lipton Tea) Decoction on Some Plasma Electrolytes and Creatinine Concentration in Female Albino Rats

DOI : https://doi.org/10.36349/easms.2021.v04i04.002

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Electrolytes are essential substances in the body required for cell function and cell signalling. The study investigated the effects of Citrus aurantifolia (lime) and Camellia sinensis (lipton tea) decoction on some plasma electrolytes and creatinine concentration. Twelve (12) female albino rats weighing between 150 -200g were used. The rats were divided into two groups: the control and test groups (n=6). The test group received 2ml/kg body weight of the decoction of lime and lipton tea orally thrice daily for 14days.The rats were sacrificed periodically and blood samples were obtained from the heart. Results obtained showed significant reduction in plasma levels of sodium and significant increases in plasma chloride and creatinine levels (P<0.05). The plasma potassium concentration increased in the test rats but this elevation was not statistically significant. It was thus concluded that the additive effect of decoction of lime and lipton may impair renal handling of electrolytes with consequent hyponatremia and hypercreatininemia. It is therefore suggested that this might be of therapeutic value in conditions associated with hypernatremia in humans.

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