Background: Brain Atrophy refers to the continuous loss of brain cells with the time and loss of connections between these neurons of brain tissues. Brain atrophy can be considered as the ultimate organ effect of cardiovascular risk factors. Advanced brain atrophy is described following hemorrhagic and ischemic stroke. Objective: To evaluate the frequency of brain atrophy and risk factors in stroke patients. Materials and Methods: This cross-sectional study was conducted on 150 patients having ischemic and hemorrhagic stroke between the periods of March 2020 to February 2021. The data was collected from the emergency department of Tertiary care Government hospital. The patients included were 68 males & 82 females examined on Computed Tomography. Changes of Evans Index were taken as a marker of brain atrophy on Computed Tomography. Results: Out of 150 stroke patients, 79 patients (49=males and 30= females) had brain atrophy with a mean age of 55.51. In Atrophic patients, 49 had hypertension, 30 had diabetes mellitus, 67 had ventriculomegaly, 39 had seizures, 42 had infarction, 66 had cognitive impairment, 18 had Depression, 66 had ischemic, and 13 had a hemorrhagic stroke. Conclusion: In conclusion, post-stroke consequences lead to brain atrophy and are also associated with various risk factors. In Ischemic stroke, brain atrophy is more prevalent than in hemorrhagic stroke.