EAS Publisher | In- vitro Antidiabetic and Anthelmintic Activity of Hydroalcoholic Extract of Impatiens Balsamina Roots

In- vitro Antidiabetic and Anthelmintic Activity of Hydroalcoholic Extract of Impatiens Balsamina Roots

DOI : https://doi.org/10.36349/easjpp.2021.v03i02.001

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Abstract: Impatiens balsamina roots were collected, dried and grinded to a corase powder. The hydroethanolic extract was prepared by hot percolation technique using Soxhlet Apparatus. The prepared extract was then evaluated for its preliminary and phytochemical screening. The phytochemical screening reveals the presence of several secondary metabolites like flavonoids, saponins, tannins, phenols, glycosides, terpenoids. The extract was evaluated for in-vitro antidiabetic activity using alpha-amylase inhibition method using Acarbose as a standard. The extract has shown its IC₅₀ value at 0.316±0.002 mg/ml, while Acarbose having IC50 value at 0.206±0.001 mg/ml. The extract was further tested for anthelmintic activity by adulticidal activity using Albendazole as a standard. The extract exhibited significant anthelmintic activity and was dose dependent.

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