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A Clinical Study on Role of Single Dose Intradermal Triamcinolone Infiltration in Preventing Hypertrophic and Keloid Scarring at Skin Grafting Donor Site

DOI : https://doi.org/10.36349/easjms.2020.v02i11.003
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Background: "Hypertrophic scars" are excessive scars in which the dense fibrous tissue does not extend beyond the borders of the original wound or incision. They tend to be wider than necessary for normal wound healing to occur. Intraoperative and postoperative intralesional steroid therapy following excision has been shown to reduce recurrence to below 50 percentage. Materials and Methods: This is prospective and descriptive study conducted in the Department of General Surgery at Surabhi Institute of Medical Sciences over a period of 1 year. Patients who needed therapeutic split skin grafting for various elective and emergency plastic surgery procedures are considered in the study. 4 months is the study period. 30 patients who need more than 20X10 cm area of split skin grafting to resurface the defects are being included in the study. Results: Among the study group, 67% were post burn contracture raw areas, 30% posttraumatic raw areas and 3% post infective raw areas. Among 30 donor site steroid injection sites 9 are hyperpigmented(dark), 7 are hypo pigmented and 14 are similar in colour with surrounding skin compared to 15 (hyper),10 (hypo), 5 (iso) respectively at donor site control areas. Mean value of normal skin thickness is 1.69, test site skin thickness is 2.20 and at control site skin thickness is 2.60. Hypertrophic scar occurred in 46% cases at kenacort injection site & in 64% of cases at test site have scars comparable with adjacent normal skin. Conclusion: In our study showed reduced scar dimensions, height, better scar texture, color match, and better symptomatic improvement with minimal dose related drug induced side effects. There seemed to be a better aesthetic and symptomatic outcome in skin grafting donor sites by using per operative intra lesional triamcinolone acetate injection after harvesting skin grafting, with respect to pigmentation and thickness.

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Dr. Afroza Begum

Lecturer, Dept. of Pharmacology and Therapeutics, Shaheed Monsur Ali Medical College & Hospital, Uttara, Dhaka-1230, Bangladesh

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