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“Comparison of Silodosin (8 Mg) Versus Tamsulosin (0.4 Mg), Both in Terms of the Stone Expulsion Rate and the Time to Stone Expulsion”

DOI : https://doi.org/10.36349/easms.2021.v04i02.006
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Abstract: Background: Ureteral stones account for 22% of all urinary tract stones with 68% of them being located in the distal ureter. Conservative management strategies such as observation or medical expulsive therapy (MET) using pharmacological agents to facilitate spontaneous passage of ureteral stones have gained popularity in the management of ureteral stones during the recent years. Objectives: To compare the efficacy of silodosin (8 mg) versus tamsulosin (0.4mg), both in terms of the stone expulsion rate and the time to stone expulsion. Patients and Methods: A prospective and randomized controlled study was conducted in the department of Urology, National Institute of Kidney Diseases & Urology (NIKDU), Dhaka, Bangladesh. Starting from October 2018, till September 2019; a total of 96 patients (M=56; F=40) who were between age group of 18–50 years, who had unilateral, non–impacted, uncomplicated middle or lower and loweror middle ureteral stones which were ≤ 1cm and ≤0.9cm were enrolled in a prospective study and they were randomized into two groups. Group 1 received tamsulosin (0.4mg)................

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Dr. Afroza Begum

Lecturer, Dept. of Pharmacology and Therapeutics, Shaheed Monsur Ali Medical College & Hospital, Uttara, Dhaka-1230, Bangladesh

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