EAS Publisher | Tremor as a Rare Undesirable Effect of Azathioprine in Remission Patient with a Pancolonic Ulcerative Colitis Disease

Tremor as a Rare Undesirable Effect of Azathioprine in Remission Patient with a Pancolonic Ulcerative Colitis Disease

DOI : https://doi.org/10.36349/easjms.2021.v03i02.003

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Abstract: Here, we report a 18 year-old man presented with tremor. The patient had a history pancolonic ulcerative colitis and he had been on corticosteroid in degression and azathioprine (AZA). He had no history of other medications, herbal or alcohol; no other diseases were diagnosised and no family history of note. The patient presented 1 month after taking AZA 2 kg/mg/day Involuntary, rhythmic movements and twitching of hands. Physical examination was normal. Biological tests and Electromyogram (EMG) were in favor of a physiologic tremor which is probably of toxic origin, and retain the diagnosis of tremor secondary to adverse effects of AZA. The outcome was favorable the day after stopping AZA. Despite its rarity, the tremor remains a significant side effect due to the socioeconomic effect that it induces.

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