EAS Publisher | Evaluation of Moringa Oleifera Lam Leaves (Moringaceae) Diets Against Induced Anemia in Wistar Rats

Evaluation of Moringa Oleifera Lam Leaves (Moringaceae) Diets Against Induced Anemia in Wistar Rats

DOI : https://doi.org/10.36349/easjnfs.2020.v02i03.004

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The effect of oleifera leaves diets against anemia was investigated in Wistar rats. Three groups of six rats each were formed. Moringa Hemolytic anemia was induced in rats by phenylhydrazine at a dose of 40 mg/kg body weight intraperitoneally for two successive days. The rats, which received phenylhydrazine were subjected to Ranferon® (Reference substance) and two régimes food P50% and P100% contained respectively 50% and 100% of sheet Moringa oleifera from day 2 (D2) until the end of the experiment to day 28 (D28). Blood was taken from all the rats to days D0, D2, D5, D14 and D28. Diets made from leaves of Moringa oleifera (P50% and P100%) and Ranferon® have significantly restored the red blood cell parameters changed by phenylhydrazine. In addition, P50% provided better values of erythrocyte parameters than P100%. However, no significant change in body weight was observed. This study revealed that these diets based on Moringa oleifera leaves has excellent therapeutic efficacy, thus confirming the use of this dietary supplement in the treatment of anemia.

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