Abstract: Background: Breastfeeding is the act of milk transference from mother to baby that is needed for the survival and healthy growth of the baby into an adult. It was observed during the clinical posting that many breastfeeding mothers that attend this primary health care centres encounter a lot of challenges in the course of breastfeeding their babies hence many stopped breastfeeding at early stage. Consequently, this study aim to determine the effect of nursing intervention on lactation- related problems among nursing mothers. Materials and methods: A quasi-experimental design was conducted with multistage sampling to select sample size (n= 36). A self-constructed questionnaire was used to measure the effect of nursing intervention on lactation-related problems. Data were analysed using descriptive statistics, and t-test at 0.05 levels of significance, through statistical package for the social science software. Results: The result showed that the knowledge of mothers on breastfeeding procedure with means (6.888 ±1.808). It also shows that the t-test of the pre and post knowledge on the following areas; procedure for breastfeeding (t=2.11, p= 0.005), breastfeeding problems (t = 9.17, p=0.001). Conclusion: The training was effective in improving the level of knowledge of breastfeeding procedure and breastfeeding-related problems. Based on the above findings, it is recommended that the government should help in minimizing these breastfeeding-related problems by organizing seminars, workshop and extension services to enlighten women on breastfeeding problems and early prevention.