Abstract: Present study aimed at finding out the interpersonal social support and perceived depression among under graduate college students of Kolkata during unlock phase of covid-19 lockdown. Two random samples of 200 participants (100 males & 100 females) aged 18 to 20 years residing in Kolkata were selected. The Beck Depression Inventory – Second Edition (BDI-II) and Interpersonal Support Evaluation List (shortened version) along with a general information schedule were administered on selected samples through online. Findings suggest that the as female college students scored higher in depression than male students and in case of social support female college students scored comparatively less than male students during unlock phase II for Covid-19 pandemic. Social support can be considered to be protective force against depression and there was a negative spiral between social support and depression. Results also confirmed that students are less depressed when they get more social support and especially the tangible support. Persons with strong social support are better able to cope with stressors, whereas those with less support may be more vulnerable to the adverse effects of stress, such as depression.