Abstract: Background: The growth and development of children will vary from one child to another. Development focuses on changes that occur gradually from the lowest level to the highest and most complex levels through the process of maturation and learning. Development relates to changes in quality, including an increase in individual capacity to function which is achieved through a process of growth, maturation, and learning. Subjects and Method: This study aims to determine knowledge, change attitudes and behavior of parents regarding Stimulation, Detection, and Early Intervention for children aged 1-5 years at Kenarilang Health Center, Alor.Descriptive research data collection based on cross sectional approach. The population taken in this study was all healthcare center’s cadres and mothers who have children aged 1-5 years who live in the working area of Kenarilang Health Center, Alor, totaling 252 people. The technique for determining the sample is proportional random stratification. The number of samples used in this study was 50 samples. Results: Most of the respondent’s as many as 27 people (54.0%) had a lack of ability to stimulate growth and development, as many as 42 people (84.0%) had a good ability to detect growth and development, and 46 people (92.0%) had good abilityat interventions for growth and development. Conclusion: Most of the respondents have less ability to stimulate growth and development. Most of the respondents have less ability to detect growth and development. Most of the respondents have a good ability in conducting growth and development interventions.