Abstract: Background: In era of increased air travel, airport security screening measures has been increased. A lot of anxiety to the patient that may trigger an alarm at airport securities post-surgery. The purpose of this study is to find out experiences of patients after total knee arthroplasty (TKA) passing through airport security. Methods: A retrospective case series of 250 TKA patients in a single high-volume center from January 2017 to January 2019, who had passed through airport security and met inclusion criteria. Patients were contacted during their regular follow ups or via phone. The patients were asked for alarm trigger, perceived inconvenience, whether security officials asked to show documentation regarding prosthesis, and any extra screening procedures check measures. Results: Out of 250 patients, 52 patients met inclusion criteria travelling by airplane. 27 patients reported alarm trigger. 7 patients had to undergo additional security check measures. 43% of the patients believed that having their TKA increased the inconvenience while traveling. Conclusions: This study provides information to surgeons regarding airport travel post TKA. Patients can be counselled regarding the inconvenience and to be prepared for delays in airport and to be prepared to present documentation of their prosthesis.