Abstract: Analysis of factors affecting the achievement of complete basic immunization for babies at the Weliman Public Health Center, Malaka was conducted to analyze the implementation of the immunization program. This research is a quantitative study using a cross sectional design. The sample in this study were mothers who had babies aged 9-12 months at Weliman Public Health Center, totaling 97 respondents and were taken using purposive sampling technique.Data analysis used simple logistic regression and multiple logistic regression. The results of the bivariate analysis showed that there was an influence of predisposing factors, namely mother’s knowledge (p = 0.016), mother’s attitude (p = 0.019), mother’s education (p = 0.001), and mother’s occupation (p = 0.000). The results of the multivariate analysis test showed that there was an effect of mother’s attitudes (p = 0.039), mother’s education (p = 0.002), and mother’s work (p = 0.008) on this.The variable with the highest Exp (B) value is mother’s education (7,571). Factors that influence the achievement of complete basic immunizationfor babies at the Weliman Public Health Center, Malaka are mother's knowledge, mother's attitude, mother's education, mother's job. Therefore, it is necessary to make efforts to improve the quality of health services by conducting regular evaluations of health workers, holding training and increasing promotional and preventive efforts by conducting IEC for mothers and families.