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Comparison of Ultrasonography with Magnetic Resonance Imaging for the Diagnosis of Liver Steatosis

DOI : https://doi.org/10.36349/easjrit.2020.v02i06.006
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Abstract: Background: Nonalcoholic fatty liver disease ranges from simple steatosis, steatohepatitis—to advanced fibrosis and cirrhosis. It has great significance in medical practise as an increasingly recognized condition globally. Early detection and quantification to prevent its sequelae is necessary. Aims: We are keen to investigate minimally invasive technique to bring for the clinicians, a socio-economic issue of importance to the field of Radiology. Objective: To compare ultrasound with MRI for the diagnosis of liver steatosis. Methods: A prospective study was carried out at Radiology Department, IDC. Study duration: November 2018 - May 2019. 86 participants, aged 14-86 years, of either gender, with suspicion of steatosis were selected, after satisfying inclusion and exclusion criteria. Steatosis was confirmed utilizing Complex-based technique with MRI. For ultrasound, conventional sonographic signs criterion was used. Results: 88 consecutive patients, (43 females and 45 males) mean age (48.88 years). MRI-PDFF revealed steatosis grade 0 (normal) in 40.9% cases, 35.2%, 18.2% and 5.7% in grade 1, 2 and 3 accordingly. While ultrasound revealed grade 0 in 26.1% cases and 44.3%, 25% and 4.5% in each respective grade. Sensitivity of ultrasound amplified as amount of hepatic fat gradually increased, from 58.33% (minimal steatotic cases) to 93.75% and 100% respectively (moderate to severe cases). Specificity remained between 73.68% to 98.82% throughout all cases. Conclusion: Ultrasound correlated well with MRI in moderate to severe hepatic steatosis, with mild degrees its specificity is reduced owing to other causes of liver injuries. Subjects practising unhealthy diet, hypertensive plus diabetics are more prone to develop steatosis. Thus its an acceptable modality for steatosis diagnosis, if severity/grading is neglected.

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Dr. Afroza Begum

Lecturer, Dept. of Pharmacology and Therapeutics, Shaheed Monsur Ali Medical College & Hospital, Uttara, Dhaka-1230, Bangladesh

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