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A Rare Case of Non-Syndromic Multiple Non-Ossifying Fibromas

DOI : https://doi.org/10.36349/easjrit.2020.v02i06.001
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Abstract: Syndromic Multifocal non-ossifying fibromas have been reported in patients with the Jaffe–Campanacci syndrome and in patients with Type 1 neurofibromatosis[1-3]. Evans and park reported a rare case of three members of a family with the existence of multiple, symmetrical, non-ossifying fibromatosis without associated neurofibromatosis [5]. Here we report a rare case of non-syndromic multiple non-ossifying fibromas. A 23-year-old male complained of bowing deformity in the Right knee for 10 years. The deformity was insidious in onset, gradually progressive on nature, and made him sit with a wide base. Initially, the base was non-progressive with minimal distance between the two feet but now the distance has increased to the length of a brick. There was no history of pain, trauma, or difficulty to perform routine activities. On examination, Genu Valgum of Right knee was diagnosed and the disappearance of Deformity was noted during flexion of the knee. There were no Café-au-lait spots or other signs of neurofibromatosis. Radiograph of the Knee revealed lucency in the distal end of the Right femur. Differential diagnoses considered were Fibrous cortical defects and Non-ossifying Fibromas. MRI of the Right knee revealed multiple well defined bubbly lytic lesion with sclerotic margin and eccentrically along the cortex in the distal femur. A similar lesion was seen in the proximal tibia. Later bone curettage was performed and histopathology examination revealed findings consistent with non-ossifying fibroma.Here we present a rare case of non-syndromic multiple non-ossifying fibromas.

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Dr. Afroza Begum

Lecturer, Dept. of Pharmacology and Therapeutics, Shaheed Monsur Ali Medical College & Hospital, Uttara, Dhaka-1230, Bangladesh

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