The study was undertaken to determine the presence and concentration of some heavy metals in selected tissues of cattle slaughtered from southern agricultural zone of Nasarawa state using Atomic Absorption Spectrophotometer (AAS). Fifty samples comprising 10 each of liver, kidney, skin, intestine and muscle were collected and analyzed for the presence of Ni, Cr, Pb, Cu and Cd. Male and female cattle of two age categories (Young and Older) were sampled for the study. The mean concentration of Ni, Pb, Cu and Cd in all the sampled tissues were generally low and within the permissible limit. High levels of Cr was detected in all samples with mean concentration of 3.9926 mg/kg, 2.4440 mg/kg, 2.9909 mg/kg, 2.1688 mg/kg and 4.0100 mg/kg in intestine, kidney, liver, muscle and skin respectively. There exist significant difference (P< 0.05) in the mean concentration of Ni and Cu between young and older cattle. Higher levels of Cr, Pb and Cd was detected in the tissues of female animal than male. The result from this study indicates that cattle slaughtered from the study area are free from Cd, Cu, Ni and Pb residues, but contained high levels of Cr. Public and private sector should establish cattle ranches so as to reduce the possibility of grazing cattle in heavy metal contaminated feed and pasture.