Depression, as a disease, is common in cancer patients. It is generally observed that various cancer patients report most of the time unfolds that they are suffering from depression, although depression is a difficult task to study in cancer patients. Hence, the present study was aimed at studying the perceived depression among cancer patients with special reference to Bihar state, India. The present study is important as it has been shown that patients with depression which tend to have drastic symptoms. To achieve the objective of the present study total sample consisted of eighty (N=80) cancer patients covering cervical and breast cancer patients comprising male (n=45) and female (n=35) were selected through incidental-cum-purposive sampling technique from the Swami Vivekanand Cancer Sansthan, Darbhanga, and Mahavir Cancer Sansthan, Patna and moreover equal number of non – cancer normal people were also selected for making comparative study. Beck Depression Inventory along with biographical information blank (BIB) were administered to collect the data. Having collected the data on the items of the inventory, the individual scores were summed up for giving statistical treatment. Finally, results revealed the fact that there is higher degree of significant difference between the group of cancer patients and normal people as “t” has been found highly significant at .01 level of confidence, although significant difference has also been found among the group of male and female cancer patients. It is very interesting to point out here that Male group of Cancer patients had shown higher level of depression in comparison to female group of cancer patients. Obtained results have been discussed in detail by giving probable reasons.