Millions of children get debilitated and pass on consistently from water, sanitation, and hygiene diseases. Children‟s ability to learn may be affected by inadequate water, sanitation, and hygiene conditions in several ways. Twenty basic schools under the School Feeding Programme were randomly selected from 10 towns within the Mampong Municipality. A total of 140 pupils were randomly selected from the 20 schools for the study. Water samples were taken from each of the schools for their physicochemical and microbial quality analyses. The findings of the study revealed that most of the water used by pupils in the selected schools had microbial contamination. More than 70% of the towns had total coliforms in water samples whilst 50% of the samples had faecal coliforms. Half of the towns had both faecal and total coliform in their water samples. Total coliform values ranged from 0.67±0.58 to 37.67±19.66 cfu/100ml and faecal coliforms 4.33±4.51 – 11.67±7.64 cfu/100ml.All physicochemical parameters were within allowable limits except pH, which were below the minimum pH level in water recommended by WHO. pH levels were between 5.02±1.59 to 6.23±0.25. It appears that microbial contamination was detected were very high in the form of Total and Faecal Coliform Bacteria. And water samples were slightly acidic, compared to the WHO recommended guidelines.