Arthritis or commonly called rheumatism is a disease that attacks the joints and structures around it, rheumatism is a case that often occurs in the elderly, rheumatism is pain in the joints. Rheumatic disease is influenced by many factors such as unhealthy lifestyles, lack of movement and exercise, and lack of knowledge about rheumatism prevention. In addition to knowledge to improve the health status of rheumatism sufferers, a supportive attitude is needed, while the attitude taken by the community towards the disease. For example, related to abstinence from foods that can make rheumatism recur again, people continue to consume it even though they already know that the food makes the disease worse. This study aims to determine the relationship between knowledge and attitudes with the incidence of rheumatoid arthritis in the elderly. The research method used was an analytic survey with a cross-sectional study approach. The sample in this study is elderly who suffer from rheumatism in Manisa Village, Baranti District, Sidrap Regency. The data obtained were analyzed using the Chi-Square statistical test with significance level α = 0.05. The results of the bivariate analysis showed that there was a relationship between knowledge and attitude with the incidence of rheumatoid arthritis in the elderly with the significance of p = 0.007 and p = 0.002. It is recommended to the Manisa Health Center District. Sidrap to improve health services for the community, especially the elderly in maintaining and maintaining the health of the elderly.