Objective: Diagnostic Medical Sonography is widely used and well-tolerated tool for prostate size evaluation. This recent paper stresses the prostate size or volume of men in a community in the Shai-Osudoku district, Greater Accra region, Ghana who took part in a medical screening program organized by charity, Naa Teley Foundation. It also stresses the value of transabdominal ultrasound that utilizes basic ultrasound equipment in evaluating the size of the prostate. Method: Eighteen (18) male between the ages 38 to 78 took part in the Medical screening program organized by Naa Teley Foundation and sponsored by the Assemblies of God, Doryumu, in the Shai-Osudoku district in the greater Accra Region during the Mothers’ Day celebration. They were made to drink 500ml of water to aid in visualization of the prostate using Sonoscape A6 grey scale machine. The procedure involved transabdominal procedure which uses a transducer that sends out ultrasound waves at a frequency too high to be heard to visualize the prostate and the bladder. Result: From the sonographic findings, prostate size does not correlate with aging and irrespective of the age of men, they could have large prostate size. Out of the eighteen men screened (18), four (4) had normal prostate size < 40grams representing 22.22%. Conclusion: From the findings, every male between the ages of thirty and above is at risk of prostatic diseases. There is therefore the need to sensitize the male public on the need for healthy prostate. Ultrasound examination is easy, fast, noninvasive and reasonably accurate and therefore recommended for male population to have their prostate assessed by the ultrasound once or twice a year.