Osteoarthritis (OA) is classified as a type of joint pain which results when the breakdown of joint ligament and underlying bone occurred. This study was conducted to assess the determinants, symptoms and consequences among patients with osteoarthritis visiting Sir Ganga Ram Hospital and University of Lahore Teaching Hospital, Lahore. 100 patients with osteoarthritis were selected using non-probability convenient sampling technique. The study was completed in 4 months. With the aid standardized WOMAC tool and pretested questionnaire, the data were collected. Version 24.0 of SPSS was used to evaluate data. Findings showed that 62 % patients were females and they were more prone toward developing disease as compared to male. Female had shown high degree of pain in joints and more symptoms leading toward osteoarthritis as compared to male. Old age was a major determinant of osteoarthritis; the mean ± SD age of patients was 61year. BMI above 25kg/m2 also influence joints pain about 61 out of 100 patients was overweight and obese. The lack of awareness about disease, poor practices, sedentary lifestyle and lack of physical activity are the major factors causing joints pain. Older age, female gender, overweight and obesity, muscle weakness, joint injury, joints stiffness, low bone mineral density, and joint laxity all play role osteoarthritis growth. It was concluded that obesity, old age, females, poor dietary practices and lack of knowledge are the risk factors of osteoarthritis. Inadequate intake of calcium and vitamin D were the associated factors of arthritis.