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A Comparative Study of Sublingual, Vaginal and Oral Misoprostol in Cervical Ripening For First Trimester Abortions

DOI : https://doi.org/10.36349/EASMS.2020.v03i03.002
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Medical abortion has been investigated as a non invasive option for early abortions as it avoids the risk of anaesthesia and surgical trauma to the cervix, uterus and other organs. The main objective of the study was to compare the efficacy of misoprostol as a cervical ripening agent in first trimester through three different routes of administration before surgical evacuation. It was a prospective longitudinal study conducted in Department of Obstetrics and Gynaecology, Guru Gobind Singh Medical College, Faridkot, Punjab from Jan 2019 to Dec 2019 on 60 women seeking first trimester abortions who were given misoprostol 400 µg by sublingual, vaginal and oral routes for cervical ripening prior to surgical evacuation. It was found that cervical dilatation was better in sublingual group as compared to oral or vaginal group and the mean duration of surgery was also less in sublingual group than in vaginal or oral group. So it was concluded that sublingual misoprostol is more effective than vaginal or oral route for pre-operative cervical ripening in first trimester abortion.

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Dr. Afroza Begum

Lecturer, Dept. of Pharmacology and Therapeutics, Shaheed Monsur Ali Medical College & Hospital, Uttara, Dhaka-1230, Bangladesh

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