Background: Fingerprint patterns are unique in each individual and the chance of two persons having identical fingerprints is about one in 64 thousand millions. The fingerprint ridges formed during foetal period do not change their course or alignment throughout the life of an individual. Finger prints are useful in forensic investigation especially for identification purpose and detection of various crimes. Objectives: The present study was conducted to correlate between fingerprint patterns in ABO, Rh blood groups and to evaluate their significance. Methods: A total 186 second year MBBS students of Andhra Medical College, Visakhapatnam India, with known blood groups from age group 17-22 years male and female were included in the study. Fingerprints were obtained by Ink method. Parameters studied Loops, Whorls, Arches, composite. Results: The general distribution pattern of finger print showed high frequency (55.65%) of loops followed by whorls and arches. Blood groups majority of the subjects (45.16%) in the study were of blood group O followed by blood group B, A and AB of whom 94.08% were Rh-positive. Highest frequency of loops was seen in O positive blood group followed by B positive.Conclusion: There is an association between distribution of finger print pattern and blood groups.