Objective: To investigate Serum Uric Acid levels, HbA1c levels in patient’s withType II Diabetes mellitus and compare with normal subjects. Methodology: The present study is a case control study conducted at Navodaya Medical College Hospital and Research Centre, over a period of 1 year. 100 participants were divided into 2 different groups, Cases and Controls. Cases included 50 patients with Type II Diabetes Mellitus and controls included 50 matched participants who didn’t have Type II Diabetes mellitus, both the groups fulfilling the inclusion criteria and exclusion criteria. Serum uric acid, blood sugar levels, HbA1c levels were measured in both controls and patients. Results: The serum uric acid levels were low in cases, compared to controls (mean in cases 3.4890 mg/dl compared to 4.8600 mg/dl in controls). The HbA1c levels negatively correlated with serum uric acid, i.e.; as HbA1c increased, serum uric acid levels decreased (p value < 0.001; highly negatively correlated). Conclusion: Serum Uric Acid levels were low in patients with Type 2 Diabetes Mellitus, particularly in those who had poor glycemic control. This may be due to increased excretion of serum uric acid during hyperglycemia and glycosuria.