Background: Recent studies have shown that obesity and impaired glucose tolerance are associated with gallbladder polyps (GBP), and are currently considered risk factors for gallbladder cancer. Therefore, the prevalence of GBP seems to be increasing. However, there is less studies discussing the correlation between obesity indicators and gallbladder polyps. Purpose: This study used adult health examination data analysis to understand the association of obesity indicators with GBP. Methods: This study is a cross-sectional data analysis study. The study collected the medical examinations of a regional hospital in Kaohsiung from 2011 to 2016. Gallbladder polyps were determined by abdominal ultrasound scanning. Use waist circumference (WC), body mass index (BMI), and waist-height ratio (WHR) as the obesity indicator. All statistical analysis was performed using the SPSS 20.0 software package for Windows. Results: The higher rate of abnormal GBP was male, less than 40 years old, normal waist circumference, normal waistheight ratio, and normal BMI. Performed a logistic regression analysis. The variables included in the regression analysis are: gender, age, BMI, WC, WHR. The results show WHR and BMI are protective factor for gallbladder polyps, odds ratio and 95% (confidence interval, CI) are (OR=0.544, 95% CI=0.442-0.670) and (OR=0.782, 95%CI=0.613-0.998) respectively. Conclusions: For the obesity indicators, this study found that WHR and BMI are protective factor for GBP.