Vitamin supplementation is one such alternative therapy and the focus of our current study, which looked at the effects of vitamin C on urate levels in patients with gout. Study was conducted to determine the effects of high vitamin C intake from diet and supplements on serum uric acid concentrations during 2 months. Group of 100 adults’ nonsmokers and hyperuricemia, from both genders and aged between 20-70 yrs was selected. Vitamin C has been touted as a preventive for problems ranging from cancers to the common cold. But can a daily vitamin C supplement protect from Gout. Possibly, researchers say, but results of studies on vitamin C and gout are mixed. Vitamin C is believed to protect against gout by lowering serum urate, thought to be due to greater removal of urate through the kidneys. A modest vitamin C dose failed to reduce uric acid levels to a clinically significant degree in patients with established gout. A further study found that reduction of uric acid was significantly less in gout patients taking vitamin C compared to those who started or increased their dose of allopurinol. For every 500-milligram increase in vitamin C intake, the risk for gout fell by 17 percent. The risk dropped by 45 percent when study participants took more than 1,500 mg of vitamin C a day. Effect of vitamin C among people with gout needs further study, In addition to understanding whether there are true benefits for people with gout, the amount of vitamin C that would be ideally effective without causing some of the harmful side effects of excessive vitamin C (such as kidney stones) will also need to be determined. A new study confirms that vitamin C does indeed raise the output of uric acid, but not to a degree sufficient to make a difference in terms of reducing gout symptoms. While current treatments are successful in reducing the amount of uric acid in the blood, there are many patients who fail to reach appropriate urate levels and need additional therapies.