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A Study on Clinicopathological Spectrum of Conjunctival Lesions in Rural Tertiary Care Hospital

DOI : https://doi.org/10.36349/easms.2018.v01i03.002
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Purpose: The purpose of this study was to assess the relative frequency of epithelial lesions of the conjunctiva in rural tertiary care hospital of Mewat, Haryana. Methods: A retrospective study of 1333 consecutive cases received during one year (2017-18) at the department of Opthalmology, SHKM GMC Nalhar Nuh was performed. Excision biopsy was done in all conjunctival lesions (2.25%) and sent to department of pathology. Demographic data was retrieved from histopathological request forms and specimens were categorized and analyzed by mean percentage. The histopathologic diagnoses were categorized into benign, pre-malignant, and malignant lesions. The prevalence of various types of conjunctival lesions was calculated. Results: Of the 1333 specimens reviewed, 295 were conjunctival lesions (2.25%). Benign lesions were most prevalent (78.8%), followed by premalignant (13.8%) and malignant (7.4%) lesions. Pterygia were the most common benign lesions (69.2%), intraepithelial dysplasia constituted most cases of premalignant lesions (94.1%), and squamous cell carcinoma was the most frequent malignant lesion (93.6%). Benign lesions were the most common type of lesions in all age groups, however the prevalence of malignant lesions increased significantly with age (P < 0.001). Conclusions: Benign lesions were the most common conjunctival lesions with pterygia on top of the list, while intraepithelial neoplasia and squamous cell carcinoma were the most common premalignant and malignant lesions, respectively. Conjunctival malignant lesions were more prevalent with older age.

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Dr. Afroza Begum

Lecturer, Dept. of Pharmacology and Therapeutics, Shaheed Monsur Ali Medical College & Hospital, Uttara, Dhaka-1230, Bangladesh

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