The integrated education from secondary vocational education to undergraduate education means the integration between secondary vocational education and applied undergraduate education. Secondary vocational students can be promoted to undergraduates by upgrading examination after graduation. Automobile engine structure and principle is a compulsory professional course for undergraduate students majoring in automobile service engineer in Shanghai University of Engineering Science, and also is the core professional course of Shanghai City Science and Technology School. It is only different in teaching emphasis in different stages, but for the moment there are still lots of repetitive contents. By sorting out the knowledge points of the curriculum, designing the course contents at different stages and reforming the teaching methods on the basis of the specific course contents, the teaching effect of automobile engine structure and principle in the integrated education from secondary vocational education to undergraduate education will be greatly improved, so as to cultivate talents and promote the further development of the integrated education from secondary vocational education to undergraduate education.