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Anatomopathological Findings in Deep Second Degree Burns Locally Treated with Allogeneic Platelet Lysate

DOI : https://doi.org/10.36349/easjms.2020.v02i10.001
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Abstract: Regenerative therapies with platelet concentrate are used as they are physiological reservoirs of growth factors (FCs) and proteins, capable of accelerating tissue regeneration. The purpose of this work has been to evaluate the regenerative effect of allogenic platelet lysate through pathological findings in deep dermal burns. A cross-sectional, observational, descriptive study was carried out to determine the clinical effect of platelet lysate on tissue regeneration in 30 patients with deep dermal burns, in the Caumatology and Plastic Surgery Service, Hospital General "Dr. Juan Bruno ZayasAlfonso”, fromSantiago de Cuba, in the period from February 2013 to February 2014.The female sex prevailed in ages between 18 and 45 years, with the lower limbs standing out as the most affected region, in both groups of treatments. The application of platelet lysate favored healing and epithelialization in a shorter time than that described with conventional treatment, with minimal adverse events, without complications, achieving a better quality of the final. Histopathological findings showed that acts directly in the healing phases, stimulating early tissue regeneration.

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Dr. Afroza Begum

Lecturer, Dept. of Pharmacology and Therapeutics, Shaheed Monsur Ali Medical College & Hospital, Uttara, Dhaka-1230, Bangladesh

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