Contrastive analysis (CA) is a branch of applied linguistics that focuses on the study of two languages in contrast (Brown, D. 1984). Teaching through this method may help the students of translation and EFL learners to use language effectively, accurately and naturally. The paper aims to present a study that explores the role of CA, comparative and contrastive collocational analysis of Persian and English, to teach collocations in Persian to English translation of journalistic texts. More specifically, it tries to provide an answer to the question on whether raising awareness of students to correct English collocations through CA has any significant effect on Persian-English translation ability of Iranian undergraduate students in translating journalistic texts. Hence, this paper invited two groups of Iranian undergraduate students majoring in English translation as the experimental and control group totaling 34 to sit for the pre-test and the post-test. Having shown no significant difference between the control and the experimental group by the pre-test (t32= 0.507, p= 0.616) regarding collocational knowledge of the participants, the study showed that applying CA led to a significant difference between the two groups in the post-test (t32= 11.56, p= 0.000).